Ten percent of SNPs that have been found to be positively selected as per the dbPSHP are within a 7 Megabase region on chr 2. This one region is very different from all other regions that have atleast 100 positively selected SNPs in that it has more than 1500 such variants.
1 154500000 167400000 121
10 100100000 113400000 108
12 52200000 62400000 125
14 59800000 70900000 117
15 62900000 79100000 121
17 50350000 64950000 125
18 63400000 67900000 135
2 62400000 75750000 131
2 95500000 101450000 111
2 131100000 137750000 1581
2 175250000 181150000 150
2 194600000 201750000 150
22 28200000 43700000 106
5 9800000 15600000 111
5 106700000 113850000 108
6 25050000 40450000 144
9 97850000 101000000 106
9 122600000 135200000 168
If so many positively selected variants are within such a short distance of each other, can they be considered independent events? Should methods that estimate selection coefficient's consider the cumulative value or just per variant estimates?
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